Test results from Dr. Kwak-Kim

Just got to the hotel from my apt with Dr. Kwak-Kim in IL. Tired and overwhelmed but I am going to try to explain what is wrong ...

1. Blood clotting issues - most of the testing came back ok except for...
PAI-1: (it came back as homozygous mutated so I inherited this disorder from both of my parents) normal is 4-43 and mine is at 70. This puts me at risk for thrombotic stroke, myocardial infarction, venous thrombosis, diabetes and pregnancy issues.
Protein C: was elevated normal is 70-180 and mine is 200
Factor XIII V 34L Gene Polymorphism: is heterozygous mutated, which means I have inherited that blood clotting disorder from 1 of my parents.
(TREATMENT) Metformin (which I am already on), VIT E 400 units daily, Fish Oil 1200mg daily, Diet, Exercise, Baby Asprin 81mg daily. During my FET I will have to do Lovanex Shots daily to thin the blood and also during pregnancy.
I do not have the MTHFR but I did show that for my Homocysteine levels that I am at 10.2 and she wants them at more like 9. This test shows I am not absorbing folic acid and vitamins like b-6 b-12 properly even though I supplement so that combined with my other clotting issues means it needs to be addressed. (TREATMENT) she is putting me on Metanx http://www.metanx.com/learn-about-metanx/

2. DHEA level was LOW - normal is 102-1185 mine was at 81 (TREATMENT) a month before FET and leading up to transfer I need to supplement with 25mg of DHEA. Being low is also connect to thyroid function. http://www.womentowomen.com/adrenalhealth/dhea-naturalandsupplementation.aspx

3. VIT D was borderline normal on the low side so she wants me to supplement with 2,000IU a day.

4. Thyroid - my u/s showed a normal thyroid
Blood work though was not normal. THS was 4.81 (the highest it ever has been and reason why my hair is falling out too) Normal is 0.47 - 4.68 but for ttc you need it at 2.0 or below. So my thyroid is working to hard and is starting to fail. (TREAMENT) Starting me on Synthroid 24mg, then blood test in 2wks see if levels are going down adjust meds, then blood at 4wks. During our FET she wants it tested every single week.

5. NK Killer cells - where elevated slightly and did respond and where lowered with IVIG. The TH1/TH2 (inflamation) was high at 35.0 normal is 13.2 - 30.6. (TREATMENT) see if by addressing the above issues these lower,(so retest in 5-6wks) otherwise start predisone at least 2 weeks before our FET and maybe IVIG too.

Everything else came back at normal. No autoimmune issues. Normal blood panel etc.

So right now I got to get on medications and deal with the thyroid, lack of my body absorbing vitamins, keep on my diet, exercise and go to my family dr. for bp. In another 5-6wks I go back and we see where my levels are at and then make a plan for FET. She wants me to get my RE to write up what he would want me to do then she will interject what she wants to add to it. Some of it I will have to travel to her to do. (which kinda sucks as it's a long trip and gas adds up)

Feel a little overwhelmed by it all but relieved I am not crazy thinking I had issues. Dr. K said for sure these things would of caused failed implantation and mc. Some of it is the genes I inherited and only so much one can do to control it. But I need to do certain things now not only for getting and staying pregnant but for my health. I can't help but feel let down by my RE about the blood clotting issues those are things that could of been found even before my first IVF as with the thyroid, they always said its normal but Dr. K says nope it is not. Glad to have a next step now, it's a start.